Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PPM1D | O15297 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735012 | 0.78 | THRB (0.35) | PPM1D | |
| SCHEMBL3611896 | 0.78 | PPM1D (0.32) | PPM1D | |
| SCHEMBL3735003 | 0.78 | THRB (0.35) | PPM1D | |
| SCHEMBL24425417 | 0.78 | PPM1D (0.32) | PPM1D | |
| SCHEMBL3735009 | 0.78 | THRB (0.35) | PPM1D | |
| SCHEMBL23190359 | 0.78 | PPM1D (0.32) | PPM1D | |
| SCHEMBL29927559 | 0.78 | PPM1D (0.34) | PPM1D | |
| SCHEMBL21307043 | 0.78 | THRB (0.35) | PPM1D | |
| SCHEMBL20696859 | 0.78 | THRB (0.35) | PPM1D | |
| SCHEMBL7261027 | 0.78 | THRB (0.35) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3427738-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2021-12-01 | — | — | EP | disclosed |
| EP-3427738-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Incorporated (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-3141252-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2018-07-25 | — | — | EP | disclosed |