Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.72 |
| ▸ | RELA | Q04206 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.52 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037431 | 0.84 | NPC1 (1.00) | NPC1RAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL4200989 | 0.84 | NPC1 (1.00) | NPC1RAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL517369 | 0.82 | CA12 (0.64) | NPC1RAB9AKMT2ASMN1; SMN2HPGD | |
| Bicarbonate SCHEMBL15225856 | 0.82 | NPC1 (0.94) | NPC1RAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL516790 | 0.81 | CA12 (0.55) | NPC1RAB9ASMN1; SMN2HPGDSMYD3 | |
| SCHEMBL14413436 | 0.81 | RAB9A (0.66) | NPC1RAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL2452482 | 0.79 | CA12 (0.54) | NPC1RAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL517027 | 0.78 | CA12 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL709454 | 0.78 | NPC1 (1.00) | NPC1RAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL3214001 | 0.78 | NPC1 (0.72) | NPC1RAB9AKMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235811-B1 | PROCESS OF PREPARING OXALAMIDES | SENOMYX INC (US) | 2018-07-25 | — | — | EP | disclosed |