Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20394334 | 0.88 | PDE10A (0.37) | PDE10A | |
| SCHEMBL20394435 | 0.83 | FEN1 (0.40) | PDE10A | |
| SCHEMBL20394463 | 0.81 | PDE10A (0.38) | PDE10A | |
| SCHEMBL20394437 | 0.81 | PDE10A (0.39) | PDE10A | |
| SCHEMBL20394300 | 0.81 | FEN1 (0.40) | PDE10A | |
| SCHEMBL20394456 | 0.81 | GRM5 (0.39) | PDE10A | |
| SCHEMBL18661504 | 0.81 | PDE10A (0.43) | PDE10AGPBAR1 | |
| SCHEMBL20394342 | 0.80 | PTGS2 (0.40) | PDE10A | |
| SCHEMBL20406577 | 0.80 | PDE10A (0.37) | PDE10A | |
| SCHEMBL18661517 | 0.80 | PDE10A (0.46) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |