Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406590 | 0.91 | FEN1 (0.37) | FEN1 | |
| SCHEMBL20406778 | 0.89 | ABL1 (0.35) | KMT2APPP1CAABL1GPBAR1PDE10A | |
| SCHEMBL20406589 | 0.81 | FEN1 (0.37) | GPBAR1FEN1 | |
| SCHEMBL20406717 | 0.79 | SYK (0.37) | GPBAR1PDE10A | |
| SCHEMBL20406446 | 0.79 | FEN1 (0.37) | KMT2APPP1CAABL1L3MBTL1PDE10A | |
| SCHEMBL18661469 | 0.79 | SYK (0.39) | GPBAR1L3MBTL1PDE10A | |
| SCHEMBL18661468 | 0.79 | SYK (0.39) | GPBAR1L3MBTL1PDE10AFEN1 | |
| SCHEMBL20394306 | 0.79 | FEN1 (0.35) | ABL1GPBAR1PDE10AFEN1 | |
| SCHEMBL20394474 | 0.79 | SYK (0.41) | ABL1GPBAR1PDE10A | |
| SCHEMBL20394383 | 0.79 | FEN1 (0.35) | KMT2APPP1CAGPBAR1L3MBTL1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |