Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406779 | 0.91 | KMT2A (0.35) | FEN1 | |
| SCHEMBL20406589 | 0.87 | FEN1 (0.37) | FEN1 | |
| SCHEMBL20406446 | 0.80 | FEN1 (0.37) | FEN1 | |
| SCHEMBL20394383 | 0.80 | FEN1 (0.35) | FEN1 | |
| SCHEMBL20394306 | 0.80 | FEN1 (0.35) | FEN1 | |
| SCHEMBL20406778 | 0.79 | ABL1 (0.35) | FEN1 | |
| SCHEMBL20406641 | 0.77 | NPC1 (0.36) | FEN1 | |
| SCHEMBL20406468 | 0.77 | P2RY1 (0.35) | FEN1RORC | |
| SCHEMBL20394408 | 0.77 | FEN1 (0.37) | FEN1 | |
| SCHEMBL20394447 | 0.74 | P2RY1 (0.40) | FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |