Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500349 | 0.82 | POLB (0.46) | POLBNCEH1SMN1; SMN2HPGDMAPT | |
| SCHEMBL18537228 | 0.81 | PTPN22 (0.47) | MAPT | |
| SCHEMBL2012785 | 0.80 | POLB (0.52) | POLBNCEH1SMN1; SMN2HPGDMAPT | |
| SCHEMBL5608955 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP2A6TSHRCYP1A2CYP2C9 | |
| SCHEMBL25156358 | 0.76 | POLB (0.50) | POLBNCEH1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL31359944 | 0.76 | POLB (0.50) | POLBNCEH1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL3268268 | 0.72 | POLB (0.50) | POLBNCEH1HPGDMAPTRAB9A | |
| SCHEMBL6470007 | 0.72 | POLB (0.50) | POLBNCEH1SMN1; SMN2HPGDMAPT | |
| SCHEMBL3670215 | 0.72 | POLB (0.50) | POLBNCEH1HPGDMAPTALDH1A1 | |
| Bromide SCHEMBL31187907 | 0.71 | POLB (0.46) | POLBNCEH1SMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2941472-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-07-25 | — | — | EP | disclosed |