Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.78 |
| ▸ | NPC1 | O15118 | 8/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | MITF | O75030 | 1/20 | 0.78 |
| ▸ | APEX1 | P27695 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | STAT1 | P42224 | 1/20 | 0.66 |
| ▸ | ACP1 | P24666 | 1/20 | 0.66 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.64 |
| ▸ | CLK1 | P49759 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19844563 | 0.88 | RAB9A (0.78) | RAB9ANPC1POLBMITFAPEX1 | |
| SCHEMBL27527831 | 0.87 | RAB9A (0.60) | RAB9ANPC1POLBMITFAPEX1 | |
| SCHEMBL14189669 | 0.85 | RAB9A (0.74) | RAB9ANPC1POLBMITFAPEX1 | |
| SCHEMBL3718317 | 0.85 | RAB9A (0.64) | RAB9ANPC1POLBMITFAPEX1 | |
| SCHEMBL10695859 | 0.83 | MAPT (0.75) | RAB9ANPC1POLBMAPTKLF5 | |
| SCHEMBL6058019 | 0.83 | LCK (0.74) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14189673 | 0.82 | RAB9A (0.70) | RAB9ANPC1POLBMITFAPEX1 | |
| SCHEMBL19844566 | 0.82 | RAB9A (0.70) | RAB9ANPC1POLBMITFAPEX1 | |
| SCHEMBL27622427 | 0.82 | MAPT (0.77) | RAB9ANPC1POLBMAPTKLF5 | |
| SCHEMBL20369717 | 0.82 | MAPT (0.77) | RAB9ANPC1POLBMAPTKLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2808383-B1 | METHOD FOR INDUCING CARDIAC DIFFERENTIATION OF PLURIPOTENT STEM CELL | UNIV KYOTO (JP) | 2018-07-25 | — | — | EP | disclosed |