⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21562205 | 0.87 | — | — | |
| SCHEMBL24969592 | 0.70 | — | — | |
| SCHEMBL21562406 | 0.65 | — | — | |
| SCHEMBL20411271 | 0.65 | — | — | |
| SCHEMBL8978419 | 0.60 | TSHR (0.36) | — | |
| SCHEMBL10593369 | 0.60 | TSHR (0.30) | — | |
| SCHEMBL24370827 | 0.59 | — | — | |
| SCHEMBL7975032 | 0.58 | — | — | |
| SCHEMBL10592177 | 0.57 | TSHR (0.35) | — | |
| SCHEMBL13770693 | 0.57 | TDP1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136620-A2 | ENDOSOMAL CLEAVABLE LINKERS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2018-07-26 | — | — | WO | disclosed |