Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | PLEC | Q15149 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20411332 | 0.87 | MEN1 (0.57) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL2790042 | 0.85 | MEN1 (0.68) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL23463081 | 0.81 | MEN1 (0.67) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL5468848 | 0.80 | USP2 (0.71) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL8930410 | 0.80 | MEN1 (0.74) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL16169467 | 0.78 | MEN1 (0.68) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL15686673 | 0.78 | MEN1 (0.68) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL12708320 | 0.78 | MEN1 (0.68) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL21760911 | 0.78 | MEN1 (0.71) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL13052179 | 0.78 | MEN1 (0.71) | MEN1KMT2AUSP2POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207284-A1 | FLUORESCENT PRODRUGS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207284-A1 | FLUORESCENT PRODRUGS | FOLH1, ENTPD5, PHPT1 | MEN1 1358/4885KMT2A 3117/4885USP2 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.