SCHEMBL2790042

SCHEMBL2790042

O=Cc1ccccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.68
▸ KMT2A Q03164 4/20 0.68
▸ USP2 O75604 3/20 0.68
▸ POLB P06746 2/20 0.68
▸ ATM Q13315 1/20 0.68
▸ PLEC Q15149 1/20 0.68
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ ALPL P05186 1/20 0.54
▸ ALPI P09923 1/20 0.54
▸ ALPG P10696 1/20 0.54
▸ HPGD P15428 3/20 0.50
▸ TP53 P04637 2/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ DNASE1L3 Q13609 1/20 0.46
▸ PRMT1 Q99873 1/20 0.46
▸ CA9 Q16790 6/20 0.44
▸ CA1 P00915 4/20 0.44
▸ CA2 P00918 4/20 0.44
▸ CDC25A P30304 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13881039 0.88 USP2 (0.64) MEN1KMT2AUSP2POLBATM
SCHEMBL14148863 0.87 USP2 (0.60) MEN1KMT2AUSP2POLBATM
SCHEMBL14093812 0.86 USP2 (0.59) MEN1KMT2AUSP2POLBATM
SCHEMBL19269681 0.86 USP2 (0.49) MEN1KMT2AUSP2POLBATM
SCHEMBL8930410 0.85 MEN1 (0.74) MEN1KMT2AUSP2POLBATM
SCHEMBL20411333 0.85 MEN1 (0.60) MEN1KMT2AUSP2POLBATM
SCHEMBL15686673 0.83 MEN1 (0.68) MEN1KMT2AUSP2POLBATM
SCHEMBL13078710 0.83 USP2 (0.56) MEN1KMT2AUSP2POLBATM
SCHEMBL13314111 0.83 USP2 (0.56) MEN1KMT2AUSP2POLBATM
SCHEMBL17385044 0.83 USP2 (0.56) MEN1KMT2AUSP2POLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100209962-A1 Tetranor PGDM: A Biomarker of PGD2 Synthesis In Vivo THE TRUSTEES OF THE UNIVERSIT OF PENNSYLVANIA 2010-08-19 — — US claimed
WO-2009043015-A1 TETRANOR PGDM: A BIOMARKER OF PGD2 SYNTHESIS IN VIVO THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-04-02 — — WO claimed
US-20230167303-A1 COLOR MATCHED AND BRIGHT FLUORESCENT MATERIALS COMPOSED OF SMALL-MOLECULE IONIC LATTICES UNIVERSITY OF COPENHAGEN (DK) 2023-06-01 — — US disclosed
EP-3604292-A1 PROCESS FOR PREPARING FLUORESCEIN QUINOID FORM Delmar Chemicals Inc. (CA) 2020-02-05 — — EP disclosed
EP-3508586-A1 METHOD AND KIT FOR DETECTING PATHOGENIC MICROORGANISM Japan Science and Technology Agency (JP) 2019-07-10 — — EP disclosed
EP-2778234-B1 LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS PROMEGA CORP (US) 2017-09-27 — — EP disclosed
US-8785682-B2 Tetranor PGDM: a biomarker of PGD2 synthesis in vivo THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2014-07-22 — — US disclosed
EP-2204371-B1 FLUORESCENT MOLECULE FROM A PROFLUOROPHORE RIKEN (JP) 2012-12-12 — — EP disclosed
WO-2012129128-A1 FLUORESCENT DYES, FLUORESCENT DYE KITS, AND METHODS OF PREPARING LABELED MOLECULES BIOTIUM, INC. (US) 2012-09-27 — — WO disclosed
US-20110178281-A1 Photocleavable Linker Methods and Compositions THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2011-07-21 — — US disclosed
US-20100234259-A1 PERFUMES CONOPCO, INC. D/B/A UNILEVER 2010-09-16 — — US disclosed
WO-2009087033-A1 GRANULES UNILEVER PLC (GB) 2009-07-16 — — WO disclosed
WO-2009047128-A1 PERFORMANCE INGREDIENTS IN FILM PARTICLES UNILEVER PLC (GB) 2009-04-16 — — WO disclosed
WO-2009047127-A1 GRANULAR DETERGENT COMPOSITIONS WITH CONTRASTING LAMELLAR VISUAL CUES UNILEVER PLC (GB) 2009-04-16 — — WO disclosed
WO-2009043015-A1 TETRANOR PGDM: A BIOMARKER OF PGD2 SYNTHESIS IN VIVO THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-04-02 — — WO disclosed
WO-2009030601-A1 IMPROVEMENTS RELATING TO FABRIC CONDITIONERS UNILEVER PLC (GB) 2009-03-12 — — WO disclosed
WO-2009030600-A1 IMPROVEMENTS RELATING TO FABRIC CONDITIONERS UNILEVER PLC (GB) 2009-03-12 — — WO disclosed
WO-2009016123-A1 IMPROVEMENTS RELATING TO PERFUMES UNILEVER PLC (GB) 2009-02-05 — — WO disclosed
WO-2008141880-A1 TRIPHENODIOXAZINE DYES UNILEVER PLC (GB) 2008-11-27 — — WO disclosed
WO-2008087031-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2008-07-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178281-A1 Photocleavable Linker Methods and Compositions NSUN2, RNGTT, METTL16 MEN1 3299/4885KMT2A 332/4885USP2 1981/4885
US-20100209962-A1 Tetranor PGDM: A Biomarker of PGD2 Synthesis In Vivo PTGDR, PTGDR2, PTGIR MEN1 4155/4885KMT2A 3662/4885USP2 2095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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