⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL4953249 | 1.00 | LMNA (1.00) | — | |
| Acetamide SCHEMBL20411579 | 1.00 | — | — | |
| Acetamide SCHEMBL6278917 | 1.00 | — | — | |
| Acetamide SCHEMBL20411649 | 1.00 | — | — | |
| Acetamide SCHEMBL2232674 | 1.00 | — | — | |
| Acetamide SCHEMBL5232 | 1.00 | — | — | |
| Acetamide SCHEMBL20411647 | 1.00 | — | — | |
| Acetamide SCHEMBL3337894 | 1.00 | LMNA (1.00) | — | |
| Acetamide SCHEMBL14990492 | 0.94 | — | — | |
| Acetamide SCHEMBL17287836 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116804007-A | Prinsene Li Wei free base hemihydrate, method for the production and use thereof | 艾库里斯有限及两合公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-109996798-B | N- [5- (aminosulfonyl) -4-methyl-1, 3-thiazol-2-yl ] -N-methyl-2- [4- (2-pyridyl) -phenyl ] -acetamide free base hemihydrate, its preparation method and use | 艾库里斯有限及两合公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20230132372-A9 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-27 | — | — | US | disclosed |
| US-20180209985-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-07-26 | — | — | US | disclosed |