SCHEMBL2041302

SCHEMBL2041302

F[C](F)C(F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
THRB P10828 1/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2042605 1.00 LMNA (0.45) LMNATHRBCA1CA2MMP1
SCHEMBL1270586 0.97 LMNA (0.40) LMNATHRB
SCHEMBL7782739 0.90 LMNA (0.47) LMNATHRBCA1CA2MMP1
SCHEMBL7783474 0.90 LMNA (0.47) LMNATHRBCA1CA2MMP1
SCHEMBL21268616 0.90 LMNA (0.47) LMNATHRBCA1CA2MMP1
SCHEMBL5692331 0.88 LMNA (0.45) LMNATHRBCA1CA2MMP1
SCHEMBL1272302 0.87 LMNA (0.35) LMNA
SCHEMBL1271591 0.76 LMNA (0.37) LMNATHRB
SCHEMBL116415 0.75
SCHEMBL31633902 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2559079-B1 COMPOSITION AND METHOD FOR PREPARATION OF ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-04-01 EP disclosed
US-10256408-B2 Composition and method for preparation of organic electronic devices MERCK PATENT GMBH (DE) 2019-04-09 US disclosed
EP-3077475-B1 COMPOSITIONS CONTAINING A POLYMERIC BINDER WHICH COMPRISES ACRYLIC AND/OR METHACRYLIC ACID ESTER UNITS MERCK PATENT GMBH (DE) 2018-07-04 EP disclosed
EP-2517274-B1 COMPOSITIONS COMPRISING POLYMERIC BINDERS MERCK PATENT GMBH (DE) 2017-05-24 EP disclosed
US-20170062725-A1 COMPOSITION AND METHOD FOR PREPARATION OF ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-03-02 US disclosed
EP-2725632-B1 USE OF COMPOSITIONS COMPRISING POLYMERIC INERT BINDERS FOR THE FABRICAITON OF LIGHT-EMITTING DIODE MERCK PATENT GMBH (DE) 2016-10-26 EP disclosed
US-20160301003-A1 COMPOSITIONS CONTAINING A POLYMERIC BINDER WHICH COMPRISES ACRYLIC AND/OR METHACRYLIC ACID ESTER UNITS MERCK PATENT GMBH (DE) 2016-10-13 US disclosed
EP-3077475-A1 COMPOSITIONS CONTAINING A POLYMERIC BINDER WHICH COMPRISES ACRYLIC AND/OR METHACRYLIC ACID ESTER UNITS Merck Patent GmbH (DE) 2016-10-12 EP disclosed
US-9178156-B2 Compositions comprising polymeric binders MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
WO-2015082037-A1 COMPOSITIONS CONTAINING A POLYMERIC BINDER WHICH COMPRISES ACRYLIC AND/OR METHACRYLIC ACID ESTER UNITS MERCK PATENT GMBH (DE) 2015-06-11 WO disclosed
EP-2517273-A1 COMPOSITIONS COMPRISING ORGANIC SEMICONDUCTING COMPOUNDS Merck Patent GmbH (DE) 2012-10-31 EP disclosed
EP-2517274-A1 COMPOSITIONS COMPRISING POLYMERIC BINDERS Merck Patent GmbH (DE) 2012-10-31 EP disclosed
WO-2011128035-A1 COMPOSITION AND METHOD FOR PREPARATION OF ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-10-20 WO disclosed
WO-2011076324-A1 COMPOSITIONS COMPRISING ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2011-06-30 WO disclosed
WO-2011076325-A1 COMPOSITIONS COMPRISING POLYMERIC BINDERS MERCK PATENT GMBH (DE) 2011-06-30 WO disclosed
CN-1975574-B Radiation sensitive resin composition SUMITOMO CHEMICAL CO 2011-06-15 CN disclosed
CN-1975574-A Radiation sensitive resin composition SUMITOMO CHEMICAL CO (JP) 2007-06-06 CN disclosed
CN-1318404-C Arylureas as Kinase Inhibitors BAYER AG (US) 2007-05-30 CN disclosed
CN-1839126-A Novel cyanopyridine derivatives for the treatment of cancer and other disorders BAYER PHARMACEUTICALS CORP (US) 2006-09-27 CN disclosed
CN-1630638-A Arylureas as Kinase Inhibitors BAYER AG (US) 2005-06-22 CN disclosed