SCHEMBL20416746

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30401170	1.00	ADORA2A (0.40)	ADORA2AADORA2BADORA1CYP19A1HDAC6
	SCHEMBL20436720	0.89	ADORA2A (0.38)	ADORA2AADORA2BADORA1CYP19A1HDAC6
	SCHEMBL20401177	0.89	ADORA2A (0.37)	ADORA2AADORA2BADORA1CYP19A1HDAC6
	SCHEMBL30401049	0.89	ADORA2A (0.37)	ADORA2AADORA2BADORA1CYP19A1HDAC6
	SCHEMBL20401388	0.88	ADORA2A (0.35)	ADORA2AADORA2BADORA1CYP19A1HDAC6
	SCHEMBL30401091	0.88	ADORA2A (0.35)	ADORA2AADORA2BADORA1CYP19A1HDAC6
	SCHEMBL20401256	0.87	CDC7 (0.36)	ADORA2AADORA2BADORA1CYP19A1HDAC6
	SCHEMBL29653551	0.87	ADORA2A (0.36)	ADORA2AADORA2BADORA1HDAC6HDAC2
	SCHEMBL20416773	0.87	ADORA2A (0.36)	ADORA2AADORA2BADORA1HDAC6HDAC2
	SCHEMBL20400595	0.86	ADORA2A (0.43)	ADORA2AADORA2BADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.