Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.85 |
| ▸ | CA12 | O43570 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.55 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12372458 | 1.00 | TDP1 (0.85) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL23745168 | 1.00 | TDP1 (0.85) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL12424058 | 0.92 | TDP1 (1.00) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL13510665 | 0.92 | TDP1 (1.00) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL10171640 | 0.92 | TDP1 (1.00) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL305707 | 0.92 | TDP1 (1.00) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL564538 | 0.92 | TDP1 (1.00) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL305706 | 0.92 | TDP1 (1.00) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL31429755 | 0.92 | TDP1 (1.00) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL17776290 | 0.92 | TDP1 (1.00) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303999-A1 | COMBINATORIAL PLATFORM FOR HIGH-THROUGHPUT POLYNUCLEOTIDE-ENCODED CATALYST DISCOVERY | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-09-28 | — | — | US | disclosed |
| WO-2018136646-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES | PROTAGONIST THERAPEUTICS, INC. (US) | 2018-07-26 | — | — | WO | disclosed |