Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20471481 | 0.88 | KDM4E (0.74) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL13374021 | 0.83 | MAPT (0.67) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL433234 | 0.79 | KMT2A (0.43) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL353564 | 0.77 | PDE4D (1.00) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL20343 | 0.76 | PDE4D (0.61) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL23001765 | 0.76 | PDE4D (0.71) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL7513038 | 0.74 | PDE4D (0.73) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL31367819 | 0.74 | PDE4D (0.73) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL4650523 | 0.73 | KDM4E (0.55) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL17777909 | 0.73 | KDM4E (0.55) | KDM4EMAPTPOLBKMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595962-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF 1-SUBSTITUTED-3-FLUOROALKYL-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012025469-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ESTERS OF 1-H-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012010692-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF 1-SUBSTITUTED-3-FLUOROALKYL-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2012-01-26 | — | — | WO | disclosed |