Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 18/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20418452 | 0.94 | STAT3 (0.62) | STAT3 | |
| SCHEMBL20418448 | 0.90 | STAT3 (0.57) | STAT3 | |
| SCHEMBL16767353 | 0.84 | STAT3 (0.69) | STAT3 | |
| SCHEMBL20418387 | 0.81 | STAT3 (1.00) | STAT3 | |
| SCHEMBL20418347 | 0.81 | STAT3 (0.69) | STAT3 | |
| SCHEMBL20418411 | 0.81 | STAT3 (0.78) | STAT3 | |
| SCHEMBL20418431 | 0.80 | STAT3 (0.63) | STAT3 | |
| SCHEMBL20418363 | 0.80 | STAT3 (1.00) | STAT3 | |
| SCHEMBL15560941 | 0.79 | STAT3 (0.60) | STAT3 | |
| SCHEMBL20418531 | 0.79 | STAT3 (0.88) | STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136935-A1 | 2-ARYLSULFONAMIDO-N-ARYLACETAMIDE DERIVATIZED STAT3 INHIBITORS | UNIVERSITY OF HAWAII (US) | 2018-07-26 | — | — | WO | disclosed |