Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 17/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15559939 | 0.89 | STAT3 (0.47) | STAT3 | |
| SCHEMBL15559484 | 0.88 | STAT3 (0.53) | STAT3 | |
| SCHEMBL15559430 | 0.88 | STAT3 (0.53) | STAT3 | |
| SCHEMBL12466793 | 0.84 | STAT3 (0.51) | STAT3 | |
| SCHEMBL20418445 | 0.79 | STAT3 (0.69) | STAT3 | |
| SCHEMBL28809685 | 0.78 | STAT3 (0.42) | STAT3 | |
| SCHEMBL28810587 | 0.76 | PTPN1 (0.44) | STAT3 | |
| SCHEMBL16767353 | 0.75 | STAT3 (0.69) | STAT3 | |
| SCHEMBL27941489 | 0.75 | STAT3 (0.42) | STAT3 | |
| SCHEMBL20418387 | 0.75 | STAT3 (1.00) | STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2854819-A2 | NEW SALICYLIC ACID DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF | The Governing Council of the University of Toronto (CA) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177534-A2 | NEW SALICYLIC ACID DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2013-11-28 | — | — | WO | disclosed |