Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1652641 | 0.89 | EPHX2 (0.43) | FAAHBACE1PDE4D | |
| SCHEMBL12239386 | 0.81 | ACHE (0.36) | ACHEBCHE | |
| SCHEMBL12239437 | 0.80 | EPHX2 (0.42) | FAAH | |
| SCHEMBL12239445 | 0.80 | MEN1 (0.35) | ACHEBCHE | |
| SCHEMBL1652806 | 0.80 | TSHR (0.36) | ACHEBCHE | |
| SCHEMBL12239433 | 0.79 | ACHE (0.36) | ACHEBCHE | |
| SCHEMBL19279416 | 0.78 | FFAR1 (0.37) | — | |
| SCHEMBL12239434 | 0.78 | ACHE (0.35) | ACHEBCHE | |
| SCHEMBL12239438 | 0.77 | ACHE (0.37) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL12239440 | 0.76 | POLB (0.34) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512237-A2 | 2 -ARYL-3 -HYDROXY-CYCLOPENTENONES AS INSECTICIDES, ACARICIDES, NEMATOCIDES AND MOLLUSCICIDES | Syngenta Participations AG (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073060-A2 | METHOD OF COMBATING AND CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-23 | — | — | WO | disclosed |