Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 4/20 | 0.33 |
| ▸ | SI | P14410 | 4/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948867 | 1.00 | TK1 (0.37) | TK1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2579718 | 1.00 | TK1 (0.37) | TK1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL12324839 | 1.00 | TK1 (0.37) | TK1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL12289253 | 1.00 | TK1 (0.37) | TK1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2041957 | 1.00 | TK1 (0.37) | TK1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL24538673 | 1.00 | TK1 (0.37) | TK1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL18023809 | 1.00 | TK1 (0.37) | TK1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL15127516 | 1.00 | TK1 (0.37) | TK1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL3169389 | 0.88 | MGAM (0.37) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10262996 | 0.88 | MGAM (0.37) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331139-B1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS (US) | 2019-04-17 | — | — | EP | disclosed |
| US-8492503-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2013-07-23 | — | — | US | disclosed |
| US-20110230618-A1 | Polymeric Alpha-Hydroxy Aldehyde and Ketone Reagents and Conjugation Method | NEKTAR THERAPEUTICS (US) | 2011-09-22 | — | — | US | disclosed |
| EP-2331139-A2 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | Nektar Therapeutics (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010030366-A2 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS (US) | 2010-03-18 | — | — | WO | disclosed |