Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19288714 | 0.72 | CYP1A2 (0.35) | — | |
| SCHEMBL23992614 | 0.70 | NOS3 (0.41) | — | |
| SCHEMBL12707249 | 0.68 | CCR1 (0.31) | — | |
| SCHEMBL23992750 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL18869349 | 0.65 | — | — | |
| SCHEMBL2032420 | 0.63 | — | — | |
| SCHEMBL2738477 | 0.63 | LIMK1 (0.45) | LIMK1 | |
| SCHEMBL2738580 | 0.63 | LIMK1 (0.45) | LIMK1 | |
| SCHEMBL19339183 | 0.62 | — | — | |
| SCHEMBL1120019 | 0.62 | HSP90AA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018134148-A1 | SUBSTITUTED DIHYDROIMIDAZOPYRIDINEDIONES AS MKNK1 AND MKNK2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-07-26 | — | — | WO | disclosed |