SCHEMBL204235

SCHEMBL204235

O=[N+]([O-])c1cc(Cl)cc(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
TDP1 Q9NUW8 1/20 0.60
CYP19A1 P11511 1/20 0.55
TSHR P16473 6/20 0.54
HSD17B10 Q99714 1/20 0.50
GPR35 Q9HC97 1/20 0.48
LMNA P02545 2/20 0.46
VCAM1 P19320 1/20 0.44
MEN1 O00255 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
MAPK1 P28482 1/20 0.43
CYP3A4 P08684 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1943699 0.94 CYP19A1 (0.62) ALDH1A1TDP1CYP19A1TSHRHSD17B10
Hydrazine SCHEMBL29052962 0.93 ALDH1A1 (0.56) ALDH1A1TDP1CYP19A1TSHRHSD17B10
Benzene SCHEMBL27733872 0.90 ALDH1A1 (0.61) ALDH1A1TDP1CYP19A1TSHRHSD17B10
Nitrogen SCHEMBL9840130 0.90 CYP19A1 (0.56) ALDH1A1TDP1CYP19A1TSHRHSD17B10
SCHEMBL29277754 0.87 CYP19A1 (0.68) ALDH1A1TDP1CYP19A1TSHRHSD17B10
SCHEMBL30721721 0.87 CYP19A1 (0.68) ALDH1A1TDP1CYP19A1TSHRHSD17B10
SCHEMBL1532381 0.84 ALDH1A1 (0.57) ALDH1A1TDP1CYP19A1TSHRHSD17B10
SCHEMBL2013681 0.84 ALDH1A1 (0.50) ALDH1A1TDP1CYP19A1TSHRHSD17B10
SCHEMBL34470321 0.84 ALDH1A1 (0.50) ALDH1A1TDP1CYP19A1TSHRHSD17B10
SCHEMBL8999906 0.84 ALDH1A1 (0.50) ALDH1A1TDP1CYP19A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119592269-A Preparation method of moisture-cured alkoxy silicon end-capped polyacrylate sealant 江苏瑞洋安泰新材料科技有限公司 2025-03-11 CN claimed
CN-118384803-A Process for preparing 3, 5-dichloroaniline by solvent-free catalytic hydrogenation of platinum-carbon catalyst 乐平市景顺实业有限公司 2024-07-26 CN claimed
CN-118109062-A One-step preparation method for synthesizing and sanding disperse orange 30 superfine liquid dye 大连理工大学 2024-05-31 CN claimed
CN-116444376-B Production process of 3, 5-dichloronitrobenzene 德兴市德邦化工有限公司 2024-01-26 CN claimed
CN-117402065-A Preparation method of 3, 5-dichloronitrobenzene 浙江闰土股份有限公司 2024-01-16 CN claimed
CN-117362182-A Hydrazine hydrate reduction process for preparing 3, 5-dichloroaniline 如东县华盛化工有限公司 2024-01-09 CN claimed
CN-117160399-A Pipeline reactor and device and method for preparing 3, 5-dichloronitrobenzene 浙江永合新材料科技有限公司 2023-12-05 CN claimed
CN-117065668-A Device and method for rapidly preparing 3,5-dichloroaniline 浙江永合新材料科技有限公司 2023-11-17 CN claimed
CN-116606213-A Method for synthesizing 3, 5-dichloroaniline by 3, 5-dichloronitrobenzene hydrazine hydrate reduction method 浙江永合新材料科技有限公司 2023-08-18 CN claimed
CN-116444376-A Production process of 3, 5-dichloronitrobenzene 德兴市德邦化工有限公司 2023-07-18 CN claimed
EP-0647472-B1 Composition of matter as Raney catalyst for hydrogenating halonitroaromatic compound and process using the same CENTRE NAT RECH SCIENT (FR) 2000-07-19 EP claimed
US-5689021-A NICKEL-ALUMINUM-MOLYBDENUM ALLOY CATALYST, FORMATION OF HALOGEN SUBSTITUTED ANILINES RHONE-POULENC CHIMIE (FR) 1997-11-18 US claimed
EP-0647472-A1 Composition of matter as Raney catalyst for hydrogenating halonitroaromatic compound and process using the same RHONE-POULENC CHIMIE (FR) 1995-04-12 EP claimed
EP-0479877-B1 METHOD OF PREPARING N-ALKYL-HALOANILINES HOECHST AG (DE) 1994-10-12 EP claimed
US-5292957-A Process for the preparation of N-alkylhalogenoanilines HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-08 US claimed
EP-0479877-A1 METHOD OF PREPARING N-ALKYL-HALOANILINES. HOECHST AG (DE) 1992-04-15 EP claimed
WO-1991000262-A1 METHOD OF PREPARING N-ALKYL-HALOANILINES HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-10 WO claimed
EP-0019789-B1 Process for the preparation of 1,3,5-trichlorobenzene HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-30 EP claimed
US-4306103-A Process for the manufacture of 1,3,5-trichlorobenzene HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-15 US claimed
EP-0019789-A1 Process for the preparation of 1,3,5-trichlorobenzene HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-10 EP claimed