Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25316068 | 0.91 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1TGFBR1CA2 | |
| SCHEMBL10895672 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1TGFBR1RXFP1 | |
| SCHEMBL10893480 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1TGFBR1RXFP1 | |
| SCHEMBL9190138 | 0.79 | — | — | |
| SCHEMBL606948 | 0.77 | — | — | |
| SCHEMBL3279553 | 0.77 | — | — | |
| SCHEMBL10895675 | 0.76 | ALDH1A1 (0.59) | ALDH1A1KDM4ETDP1TGFBR1RXFP1 | |
| SCHEMBL16025410 | 0.75 | — | — | |
| SCHEMBL28447053 | 0.74 | — | — | |
| SCHEMBL10893305 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4ETDP1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10551345-B2 | Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2020-02-04 | — | — | US | claimed |
| US-20170356877-A1 | POLY AND COPOLY(N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLIED BIOSYSTEMS, LLC (US) | 2017-12-14 | — | — | US | claimed |
| US-20120305838-A1 | Polyelectrolyte-Coated Size-Exclusion Ion-Exchange Particles | APPLIED BIOSYSTEMS, LLC (US) | 2012-12-06 | — | — | US | claimed |
| US-20100317841-A1 | Polyelectrolyte-Coated Size-Exclusion Ion-Exchange Particles | Life Technologies Corporation (US) | 2010-12-16 | — | — | US | claimed |
| US-20100051461-A1 | Poly and Copolyn(N-Vinylamide)s and their use in Capillary Electrophoresis | Life Technologies Corporation (US) | 2010-03-04 | — | — | US | claimed |
| EP-2053067-A1 | Poly and copoly (N-vinylamide)s and their use in capillary electrophoresis | Applied Biosystems Inc. (US) | 2009-04-29 | — | — | EP | claimed |
| EP-1636279-B1 | POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLIED BIOSYSTEMS (US) | 2009-02-18 | — | — | EP | claimed |
| US-20060091015-A1 | Surface modification for non-specific adsorption of biological material | APPLERA CORPORATION (US) | 2006-05-04 | — | — | US | claimed |
| EP-1636279-A1 | POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | Applera Corporation (US) | 2006-03-22 | — | — | EP | claimed |
| US-20050181378-A1 | For PCR and DNA sequencing; electrophoresis; microfluidics | APPLERA CORPORATION (US) | 2005-08-18 | — | — | US | claimed |
| US-20050025741-A1 | Copolymers with (meth)acrylamides; improved separation of polynucleotides | APPLIED BIOSYSTEMS, LLC | 2005-02-03 | — | — | US | claimed |
| WO-2004104054-A1 | POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLERA CORPORATION (US) | 2004-12-02 | — | — | WO | claimed |
| EP-0115054-B1 | BETA-ELIMINATING POLYMERS FOR DIFFUSION CONTROL IN PHOTOGRAPHIC PRODUCTS | POLAROID CORPORATION (US) | 1988-02-10 | — | — | EP | claimed |
| US-4547451-A | INTERLAYERS OF ACRYLIC ESTER COPOLYMERS | POLAROID CORPORATION, PATENT DEPT. (US) | 1985-10-15 | — | — | US | claimed |
| EP-0127787-A2 | Hydrolyzable diffusion control layers in photographic products | POLAROID CORPORATION (US) | 1984-12-12 | — | — | EP | claimed |
| EP-0115054-A2 | Beta-eliminating polymers for diffusion control in photographic products | POLAROID CORPORATION (US) | 1984-08-08 | — | — | EP | claimed |
| EP-0115053-A2 | Diffusion control layers in diffusion transfer photographic products | POLAROID CORPORATION (US) | 1984-08-08 | — | — | EP | claimed |
| US-4461824-A | POLYMERS WHICH UNDERGO ELIMINATION IN ALKALINE ENVIRONMENT | POLAROID CORPORATION (US) | 1984-07-24 | — | — | US | claimed |
| US-4458001-A | HOLD-RELEASE LAYERS | POLAROID CORPORATION (US) | 1984-07-03 | — | — | US | claimed |
| US-4288523-A | ESTER-SUBSTITUTED (METH)ACRYLAMIDE POLYMERS WITH B-ELIMINATION GROUPS | POLAROID CORPORATION (US) | 1981-09-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050025741-A1 | Copolymers with (meth)acrylamides; improved separation of polynucleotides | POLI, PCNA, POLL | ALDH1A1 3357/4885KDM4E 3657/4885TDP1 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.