Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20441155 | 0.99 | TDP1 (0.67) | LMNATDP1AKR1C3CES2CES1 | |
| SCHEMBL20424345 | 0.99 | TDP1 (0.67) | LMNATDP1AKR1C3CES2CES1 | |
| SCHEMBL20424346 | 0.99 | TDP1 (0.67) | LMNATDP1AKR1C3CES2CES1 | |
| SCHEMBL20424326 | 0.90 | TDP1 (0.71) | LMNATDP1AKR1C3CES2CES1 | |
| SCHEMBL20424327 | 0.90 | TDP1 (0.71) | LMNATDP1AKR1C3CES2CES1 | |
| SCHEMBL20424893 | 0.90 | TDP1 (0.71) | LMNATDP1AKR1C3CES2CES1 | |
| SCHEMBL20441153 | 0.89 | LMNA (0.62) | LMNATDP1AKR1C3CES2CES1 | |
| SCHEMBL20424332 | 0.87 | TDP1 (0.63) | LMNATDP1AKR1C3CES2CES1 | |
| SCHEMBL29964257 | 0.87 | TDP1 (0.63) | LMNATDP1AKR1C3CES2CES1 | |
| SCHEMBL20424331 | 0.87 | TDP1 (0.63) | LMNATDP1AKR1C3CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138369-A1 | COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF | CHEMCOM S.A. (BE) | 2018-08-02 | — | — | WO | disclosed |