SCHEMBL20425314

SCHEMBL20425314

Oc1ccc(C[C@@H](c2ccccc2)c2ccc(O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.55
ESR2 Q92731 12/20 0.55
SLC6A2 P23975 1/20 0.53
SLC6A4 P31645 1/20 0.53
SLC6A3 Q01959 1/20 0.53
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 1/20 0.50
IDO1 P14902 1/20 0.47
TDO2 P48775 1/20 0.47
SLC7A5 Q01650 1/20 0.47
TAAR1 Q96RJ0 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163773 1.00 ESR1 (0.55) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL983099 0.98 SLC6A2 (0.55) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL69283 0.93 SLC6A2 (0.55) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL231792 0.93 ESR1 (0.61) ESR1ESR2SLC6A2MEN1ALDH1A1
SCHEMBL10615463 0.90 ESR1 (0.54) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL6686176 0.89 ESR1 (0.76) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL8410262 0.87 ESR1 (0.61) ESR1ESR2SLC6A2MEN1ALDH1A1
SCHEMBL21085645 0.85 LTA4H (0.62) ESR1ESR2SLC6A2SLC6A3MEN1
SCHEMBL20694839 0.84 SLC6A2 (0.48) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL237506 0.84 SLC6A2 (0.48) ESR1ESR2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230097414-A1 HEAT RESISTANT AROMATIC POLYCARBONATE - POLYESTER COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-03-30 US disclosed
EP-4121480-A1 HEAT RESISTANT AROMATIC POLYCARBONATE - POLYESTER COMPOSITION SABIC Global Technologies B.V. (NL) 2023-01-25 EP disclosed
WO-2021186022-A1 HEAT RESISTANT AROMATIC POLYCARBONATE - POLYESTER COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-09-23 WO disclosed
EP-3802723-A1 METHOD FOR BONDING USING ONE-COMPONENT EPOXY ADHESIVE MIXTURES DDP Specialty Electronic Materials US, LLC (US) 2021-04-14 EP disclosed
EP-3802678-A1 METHOD FOR RECYCLING EPOXY-FIBER COMPOSITES INTO POLYOLEFINS Dow Global Technologies, LLC (US) 2021-04-14 EP disclosed
EP-3574034-A1 A THERMOSETTING EPOXY RESIN COMPOSITION FOR THE PREPARATION OF ARTICLES FOR ELECTRICAL ENGINEERING, AND THE ARTICLES OBTAINED THEREFROM Huntsman Advanced Materials Licensing (Switzerland) GmbH (CH) 2019-12-04 EP disclosed
WO-2018140576-A1 A THERMOSETTING EPOXY RESIN COMPOSITION FOR THE PREPARATION OF ARTICLES FOR ELECTRICAL ENGINEERING, AND THE ARTICLES OBTAINED THEREFROM HUNTSMAN ADVANCED MATERIALS LICENSING (SWITZERLAND) GMBH (CH) 2018-08-02 WO disclosed