Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.38 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.38 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758619 | 0.98 | TSHR (0.59) | TSHRTHRBMAPTSMN1; SMN2GALR3 | |
| Hydrochloric Acid SCHEMBL6300759 | 0.96 | TSHR (0.53) | TSHRTHRBMAPTSMN1; SMN2GALR3 | |
| Bromide SCHEMBL1254317 | 0.96 | TSHR (0.57) | TSHRTHRBMAPTSMN1; SMN2GALR3 | |
| Iodide SCHEMBL1255392 | 0.96 | TSHR (0.57) | TSHRTHRBMAPTSMN1; SMN2GALR3 | |
| Hydrochloric Acid SCHEMBL534137 | 0.96 | TSHR (0.57) | TSHRTHRBMAPTSMN1; SMN2GALR3 | |
| Fluoride Ion SCHEMBL1254970 | 0.96 | TSHR (0.57) | TSHRTHRBMAPTSMN1; SMN2GALR3 | |
| Chloromethane SCHEMBL10796929 | 0.94 | TSHR (0.55) | TSHRTHRBMAPTSMN1; SMN2GALR3 | |
| Methacrylic Acid SCHEMBL11703226 | 0.93 | TSHR (0.50) | TSHRTHRBMAPTSMN1; SMN2GALR3 | |
| Acetic Acid SCHEMBL22188618 | 0.93 | TSHR (0.53) | TSHRTHRBMAPTSMN1; SMN2GALR3 | |
| Sulfuric Acid SCHEMBL8098694 | 0.90 | TSHR (0.50) | TSHRTHRBMAPTSMN1; SMN2GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1993 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260061062-A1 | MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM | UNIV NEBRASKA (US) | 2026-03-05 | — | — | US | claimed |
| CN-118184288-B | Cement with low heat and low expansion coefficient and production method thereof | 西藏昌都高争建材股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119263761-B | High-performance double-slurry rapid-hardening grouting material and preparation method thereof | 四川海纳捷建科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119472194-A | Phenol-free positive photoresist stripping liquid and preparation method thereof | 浙江尚能实业股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| EP-4486508-A1 | METHODS FOR SEPARATING AND DETECTING DOUBLE-STRANDED AND SINGLE-STRANDED RIBONUCLEIC ACID (RNA) | Revvity Health Sciences, Inc. (US) | 2025-01-08 | — | — | EP | claimed |
| CN-119263761-A | High-performance double-slurry rapid-hardening grouting material and preparation method thereof | 四川海纳捷建科技有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-118785975-A | Method for separating and detecting double-stranded and single-stranded ribonucleic acid (RNA) | 瑞孚迪健康科学有限公司 | 2024-10-15 | — | — | CN | claimed |
| US-20240218186-A1 | METHOD OF PREPARING COATED PIGMENT AND WATER-BASED INK COMPOSITION CONTAINING COATED PIGMENT PREPARED THEREBY | DONG-A PENCIL CO., LTD. (KR) | 2024-07-04 | — | — | US | claimed |
| US-20240218187-A1 | METHOD OF PREPARING COATED PIGMENT AND WATER-BASED INK COMPOSITION CONTAINING COATED PIGMENT PREPARED THEREBY | DONG-A PENCIL CO., LTD. (KR) | 2024-07-04 | — | — | US | claimed |
| CN-118184288-A | Cement with low heat and low expansion coefficient and production method thereof | 西藏昌都高争建材股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| US-4353818-A | GRAFT CATIONIC COPOLYMERS; FILLERS FOR PAPER | HERCULES INCORPORATED (US) | 1982-10-12 | — | — | US | claimed |
| US-4320011-A | Oil-containing waste water treating material consisting of modified active carbon | MITSUBISHI RAYON COMPANY, LIMITED (JP) | 1982-03-16 | — | — | US | claimed |
| US-4299748-A | DISPERSION OF ACRYLIC COPOLYMERS CONTAINING AN ELECTROCONDUCTIVE COPOLYMER | DAICEL LTD. (JP) | 1981-11-10 | — | — | US | claimed |
| US-4293427-A | (METH)ACRYLAMIDE-(METH)ACRYLAMIDOSULFONIC ACID COPOLYMER OPTIONALLY CROSSLINKED | MILCHEM INCORPORATED (US) | 1981-10-06 | — | — | US | claimed |
| US-4248685-A | COPOLYMERIZING ACRYLIC ESTER CONTAINING CATIONIC NITROGEN, AND AN ACRYLIC ESTER OR AMIDE TO PRODUCE BACTERIOSTATIC FILMS OR PARTICLES | JOHNSON & JOHNSON (US) | 1981-02-03 | — | — | US | claimed |
| US-4246355-A | ACTIVATION OF AN INNER POLYMER MATRIX IMPREGNATED WITH FERROMAGNETIC MATERIAL, GRAFT POLYMERIZATION OF OUTER SHELL | ICI AUSTRALIA LIMITED (AU) | 1981-01-20 | — | — | US | claimed |
| US-4148639-A | Water-insensitive electroconductive polymers | CALGON CORPORATION (US) | 1979-04-10 | — | — | US | claimed |
| US-4111922-A | HYDROPHILIC RANDOM INTERPOLYMER FROM QUATERNARY AMMONIUM MONOMERS AND METHOD FOR MAKING SAME | JOHNSON & JOHNSON (US) | 1978-09-05 | — | — | US | claimed |
| US-4082705-A | CROSSLINKED QUATERNARY AMMONIUM ACRYLATE INTERPOLYMER | JOHNSON & JOHNSON (US) | 1978-04-04 | — | — | US | claimed |
| US-3976552-A | STARCH | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-08-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260061062-A1 | MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM | CD44, ALG1, HSF1 | CHRM1 85/4885CHRM2 267/4885CHRM3 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.