Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20426311 | 1.00 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BRARB | |
| SCHEMBL20427349 | 0.95 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BRARB | |
| SCHEMBL15020017 | 0.93 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2BRARB | |
| SCHEMBL15091900 | 0.93 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2BRARB | |
| SCHEMBL15037058 | 0.93 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2BRARB | |
| SCHEMBL15096631 | 0.93 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2BRARB | |
| SCHEMBL22449285 | 0.93 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2BRARB | |
| SCHEMBL15037035 | 0.93 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2BRARB | |
| SCHEMBL22449298 | 0.93 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2BRARB | |
| SCHEMBL22449249 | 0.93 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259823-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2019-04-16 | — | — | US | disclosed |
| US-10034886-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2018-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10034886-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | ITGB1 3369/4885ITGA4 4604/4885ITGB3 3678/4885 |
| US-10259823-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | ITGB1 3369/4885ITGA4 4604/4885ITGB3 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.