Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607781 | 0.94 | THRB (0.37) | KDM4ETDP1THRBPKMTYMS | |
| SCHEMBL23045942 | 0.89 | THRB (0.43) | KDM4ECA12CA9GLAPOLB | |
| SCHEMBL22600379 | 0.89 | ELANE (0.36) | THRBTYMSKMT2ATHRA | |
| SCHEMBL21417755 | 0.89 | ELANE (0.37) | THRBTYMSCA2THRA | |
| SCHEMBL22600377 | 0.89 | THRB (0.35) | THRBTYMSKMT2A | |
| SCHEMBL18472427 | 0.89 | ERN1 (0.43) | KDM4EGAATDP1THRBLMNA | |
| SCHEMBL18358987 | 0.88 | THRB (0.33) | THRBTYMS | |
| SCHEMBL19497335 | 0.87 | ERN1 (0.41) | KDM4EGAATHRBRAB9ALMNA | |
| SCHEMBL20343017 | 0.87 | THRB (0.39) | KDM4EGLAPOLBGAATHRB | |
| SCHEMBL18868946 | 0.85 | THRB (0.33) | THRBTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957618-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-08-01 | — | — | EP | disclosed |