Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | HPGD | P15428 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420776 | 0.82 | HPGD (0.55) | RAB9AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL20420780 | 0.79 | CA12 (0.52) | ALDH1A1HPGDKDM4ELMNANOD2 | |
| SCHEMBL20420762 | 0.78 | ALDH1A1 (0.51) | TDP1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL20420745 | 0.76 | MAOB (0.55) | TDP1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL20420750 | 0.75 | CA1 (0.52) | TDP1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL20420772 | 0.74 | ALDH1A1 (0.49) | RAB9AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL20420801 | 0.74 | HPGD (0.51) | TDP1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL20428335 | 0.72 | APP (0.52) | RAB9AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL20420786 | 0.72 | ALDH1A1 (0.52) | RAB9AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL20420790 | 0.71 | CYP2D6 (0.56) | TDP1RAB9AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354648-A1 | 4-SUBSTITUED COUMARIN DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | Guizhou Bailing Group Pharmaceutical Co., Ltd. (CN) | 2018-08-01 | — | — | EP | disclosed |