Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.37 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.37 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.37 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420809 | 1.00 | FPR1 (0.43) | FPR1TOP2AHDAC1HDAC8HDAC6 | |
| SCHEMBL20420765 | 1.00 | FPR1 (0.43) | FPR1TOP2AHDAC1HDAC8HDAC6 | |
| SCHEMBL20420746 | 0.99 | FPR1 (0.42) | FPR1TOP2AHDAC1HDAC8HDAC6 | |
| SCHEMBL20428403 | 0.96 | TP53 (0.42) | FPR1HDAC1HDAC8HDAC6TP53 | |
| SCHEMBL20420755 | 0.93 | KMT2A (0.41) | HDAC1HDAC8HDAC6ALOX15TP53 | |
| SCHEMBL20420802 | 0.92 | HDAC1 (0.42) | FPR1HDAC1HDAC8HDAC6TP53 | |
| SCHEMBL20428368 | 0.92 | HDAC1 (0.41) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL20428373 | 0.91 | HDAC1 (0.41) | HDAC1HDAC8HDAC6ALOX15TP53 | |
| SCHEMBL20428327 | 0.88 | KDM4E (0.42) | ALOX15TP53MAPTCYP3A4PTGS2 | |
| SCHEMBL20428410 | 0.88 | TSHR (0.40) | HDAC1HDAC8HDAC6TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544134-B2 | 4-substituted coumarin derivatives and preparation methods and uses thereof | GUIZHOU BAILING GROUP PHARMACEUTICAL CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
| EP-3354648-A1 | 4-SUBSTITUED COUMARIN DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | Guizhou Bailing Group Pharmaceutical Co., Ltd. (CN) | 2018-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544134-B2 | 4-substituted coumarin derivatives and preparation methods and uses thereof | MAP4, TUBA3C, ABCC1 | FPR1 3550/4885TOP2A 173/4885HDAC1 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.