Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.71 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660980 | 0.92 | DGAT1 (0.76) | DGAT1 | |
| SCHEMBL16787868 | 0.88 | DGAT1 (0.82) | DGAT1 | |
| SCHEMBL16661353 | 0.85 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL16660911 | 0.83 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL16661189 | 0.82 | DGAT1 (0.88) | DGAT1 | |
| SCHEMBL16787870 | 0.82 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL16661191 | 0.81 | DGAT1 (0.82) | DGAT1 | |
| SCHEMBL16661343 | 0.81 | DGAT1 (0.83) | DGAT1KCNH2 | |
| SCHEMBL16660985 | 0.81 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL16660859 | 0.81 | DGAT1 (0.77) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |