Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 16/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661367 | 0.91 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL20428811 | 0.90 | DGAT1 (0.45) | DGAT1AAK1 | |
| SCHEMBL21064830 | 0.90 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL18541130 | 0.89 | DGAT1 (0.47) | DGAT1AAK1 | |
| SCHEMBL16661035 | 0.81 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL16661196 | 0.81 | DGAT1 (0.57) | DGAT1 | |
| SCHEMBL16661011 | 0.80 | DGAT1 (0.58) | DGAT1AAK1 | |
| SCHEMBL16661212 | 0.79 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL20428616 | 0.78 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL20428585 | 0.78 | DGAT1 (0.49) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |