Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 17/20 | 0.82 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20428663 | 0.91 | DGAT1 (0.83) | DGAT1SCN2A | |
| SCHEMBL16649144 | 0.90 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL16649188 | 0.83 | DGAT1 (1.00) | DGAT1SCN2A | |
| SCHEMBL16660848 | 0.82 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL16790146 | 0.81 | DGAT1 (0.67) | DGAT1 | |
| SCHEMBL16660928 | 0.80 | DGAT1 (0.70) | DGAT1SCN2ANPY5R | |
| SCHEMBL16787579 | 0.80 | DGAT1 (0.79) | DGAT1 | |
| SCHEMBL16661033 | 0.79 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL16649080 | 0.78 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL16648982 | 0.78 | DGAT1 (0.78) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |