Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189908 | 0.84 | KMT2A (0.45) | POLBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL8099254 | 0.83 | KMT2A (0.50) | POLBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL106265 | 0.83 | KMT2A (0.50) | POLBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL14606391 | 0.83 | KMT2A (0.50) | POLBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL18322599 | 0.83 | KMT2A (0.50) | POLBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL868953 | 0.80 | BRD4 (0.47) | POLBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL11342867 | 0.80 | L3MBTL1 (0.40) | POLBKMT2AEPHX1HPGDLMNA | |
| SCHEMBL22534506 | 0.78 | KMT2A (0.45) | POLBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL6321838 | 0.78 | EPHX1 (0.48) | POLBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL13618451 | 0.78 | L3MBTL1 (0.44) | POLBKMT2AEPHX1HPGDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |