Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21064883 | 0.93 | DGAT1 (0.42) | DGAT1CRHR1DPP4DPP7 | |
| SCHEMBL16661248 | 0.84 | DGAT1 (0.56) | DGAT1CRHR1DPP4DPP7 | |
| SCHEMBL20428828 | 0.84 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL21064879 | 0.82 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL16661257 | 0.75 | DGAT1 (0.38) | DGAT1CRHR1 | |
| SCHEMBL18552911 | 0.75 | DGAT1 (0.38) | DGAT1CRHR1DPP4DPP7 | |
| SCHEMBL16661005 | 0.73 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL16661275 | 0.70 | PDE10A (0.34) | DGAT1 | |
| SCHEMBL16661043 | 0.69 | DGAT1 (0.49) | DGAT1CRHR1DPP4DPP7 | |
| SCHEMBL16661247 | 0.68 | DGAT1 (0.36) | DGAT1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |