Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29579430 | 0.83 | DGAT1 (0.43) | DGAT1USP30LPLLIPGNOTUM | |
| SCHEMBL196887 | 0.83 | DGAT1 (0.43) | DGAT1USP30LPLLIPGNOTUM | |
| SCHEMBL16787857 | 0.82 | DGAT1 (0.40) | DGAT1USP30LPLLIPGNOTUM | |
| SCHEMBL16787859 | 0.79 | DGAT1 (0.49) | DGAT1USP30AAK1HIF1A | |
| Methane SCHEMBL28521588 | 0.77 | DGAT1 (0.41) | DGAT1USP30LPLLIPGHIF1A | |
| SCHEMBL20791777 | 0.76 | DGAT1 (0.40) | DGAT1USP30LPLLIPG | |
| SCHEMBL29601147 | 0.73 | USP30 (0.39) | DGAT1USP30LPLLIPG | |
| SCHEMBL20364714 | 0.73 | USP30 (0.39) | DGAT1USP30LPLLIPG | |
| SCHEMBL22558630 | 0.73 | DGAT1 (0.40) | DGAT1USP30LPLLIPGAAK1 | |
| SCHEMBL17129006 | 0.71 | DGAT1 (0.53) | DGAT1LPLLIPGHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |