Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2042898 | 1.00 | PRF1 (1.00) | PRF1 | |
| SCHEMBL14761214 | 1.00 | PRF1 (1.00) | PRF1 | |
| SCHEMBL2054373 | 0.89 | PRF1 (1.00) | PRF1 | |
| SCHEMBL14761573 | 0.89 | PRF1 (1.00) | PRF1 | |
| SCHEMBL2054374 | 0.89 | PRF1 (1.00) | PRF1 | |
| SCHEMBL14761614 | 0.82 | PRF1 (1.00) | PRF1 | |
| SCHEMBL14761616 | 0.82 | PRF1 (1.00) | PRF1 | |
| SCHEMBL2019635 | 0.81 | PRF1 (0.68) | PRF1 | |
| SCHEMBL12633692 | 0.80 | PRF1 (1.00) | PRF1 | |
| SCHEMBL14761477 | 0.80 | PRF1 (1.00) | PRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2515903-A1 | COMPOUNDS, PREPARATIONS AND USES THEREOF | Peter MacCallum Cancer Institute (AU) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011075784-A1 | COMPOUNDS, PREPARATIONS AND USES THEREOF | PETER MACCALLUM CANCER INSTITUTE (AU) | 2011-06-30 | — | — | WO | disclosed |