Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14903761 | 1.00 | TAAR1 (1.00) | TAAR1HTR1ADRD2HTR7KEAP1 | |
| SCHEMBL12644088 | 0.87 | TAAR1 (1.00) | TAAR1HTR1ADRD2HTR7KEAP1 | |
| SCHEMBL14903739 | 0.87 | TAAR1 (1.00) | TAAR1HTR1ADRD2HTR7KEAP1 | |
| SCHEMBL14903730 | 0.87 | TAAR1 (1.00) | TAAR1HTR1ADRD2HTR7KEAP1 | |
| SCHEMBL28945875 | 0.87 | TAAR1 (0.77) | TAAR1HTR1ADRD2HTR7KEAP1 | |
| SCHEMBL28964100 | 0.85 | TAAR1 (0.74) | TAAR1HTR1ADRD2HTR7KEAP1 | |
| SCHEMBL6551697 | 0.84 | TAAR1 (0.72) | TAAR1HTR1ADRD2HTR7KEAP1 | |
| SCHEMBL2037558 | 0.81 | TAAR1 (0.76) | TAAR1HTR1ADRD2HTR7KEAP1 | |
| SCHEMBL14903760 | 0.81 | TAAR1 (0.76) | TAAR1HTR1ADRD2HTR7KEAP1 | |
| Hydrochloric Acid SCHEMBL28514686 | 0.80 | TAAR1 (0.74) | TAAR1HTR1ADRD2HTR7KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507245-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011069063-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | WO | disclosed |