SCHEMBL20429730

SCHEMBL20429730

O=C1OC(=O)C(c2ccccc2)C1c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.46
EDNRA P25101 1/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
HTR2B P41595 1/20 0.41
GAA P10253 2/20 0.39
ABL1 P00519 1/20 0.39
RIN1 Q13671 1/20 0.39
CA2 P00918 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
ALOX15 P16050 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CTRC Q99895 1/20 0.37
RAB9A P51151 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24610064 0.84 SMN1; SMN2 (0.39) SMN1; SMN2EDNRAMAPTLMNATP53
SCHEMBL19201565 0.82 RAB9A (0.39) SMN1; SMN2MAPTLMNATP53CYP1A2
SCHEMBL16866268 0.82 RAB9A (0.39) SMN1; SMN2MAPTLMNATP53CYP1A2
SCHEMBL21860423 0.82 RAB9A (0.39) SMN1; SMN2MAPTLMNATP53CYP1A2
SCHEMBL16870171 0.82 RAB9A (0.39) SMN1; SMN2MAPTLMNATP53CYP1A2
SCHEMBL18674140 0.82 RAB9A (0.39) SMN1; SMN2MAPTLMNATP53CYP1A2
SCHEMBL18674132 0.80 SMN1; SMN2 (0.36) SMN1; SMN2EDNRAMAPTHTR2BGAA
SCHEMBL10707636 0.79 MAPT (0.52) SMN1; SMN2MAPTLMNATP53CYP1A2
SCHEMBL4262122 0.75 SMN1; SMN2 (0.43) SMN1; SMN2EDNRAMAPTLMNATP53
SCHEMBL10843954 0.75 SMN1; SMN2 (0.65) SMN1; SMN2EDNRAMAPTLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798627-A Method for preparing hydroxyl-terminated high molecular polyester polyol without metal catalyst and polyester polyol 北京高盟新材料股份有限公司 2025-04-11 CN claimed
CN-118852022-B Gemini quaternary ammonium salt antibacterial agent, preparation thereof and application thereof in antibacterial polyester synthesis 浙江大学 2025-03-28 CN claimed
CN-118852022-A Gemini quaternary ammonium salt antibacterial agent, preparation thereof and application thereof in antibacterial polyester synthesis 浙江大学 2024-10-29 CN claimed
US-11912818-B2 Method for synthesizing aromatic-aliphatic copolyester without catalyst and product thereof ZHEJIANG UNIVERSITY (CN) 2024-02-27 US claimed
US-20230391948-A1 METHOD FOR SYNTHESIZING AROMATIC-ALIPHATIC COPOLYESTER WITHOUT CATALYST AND PRODUCT THEREOF ZHEJIANG UNIVERSITY (CN) 2023-12-07 US claimed
WO-2022148259-A1 METHOD FOR SYNTHESIZING AROMATIC-ALIPHATIC COPOLYESTER WITHOUT CATALYST, AND PRODUCT THEREOF 浙江大学 2022-07-14 WO claimed
CN-112831033-B Method for synthesizing aromatic-aliphatic copolyester without catalyst and product thereof 浙江大学 2022-03-22 CN claimed
CN-111978528-B Method for synthesizing aromatic polyester without catalyst and product thereof 浙江大学 2021-11-09 CN claimed
CN-112831033-A Method for synthesizing aromatic-aliphatic copolyester without catalyst and product thereof 浙江大学 2021-05-25 CN claimed
CN-111978528-A Method for synthesizing aromatic polyester without catalyst and product thereof 浙江大学 2020-11-24 CN claimed
CN-110790906-A Method for synthesizing high molecular weight aliphatic polyester without catalyst and product thereof 浙江大学 2020-02-14 CN claimed
CN-122071574-A Novel PEAT material 元素驱动(杭州)生物科技有限公司 2026-05-22 CN disclosed
WO-2025124564-A1 POLYESTER SYNTHESIS BASED ON ASPARTIC ACID MODIFICATION 元素驱动(杭州)生物科技有限公司 2025-06-19 WO disclosed
WO-2025108372-A1 TEMPERATURE-RESISTANT POLYMER AND PREPARATION METHOD THEREFOR, AND USE OF CYCLIC IMIDE DIOL COMPOUND 元素驱动(杭州)生物科技有限公司 2025-05-30 WO disclosed
WO-2025108371-A1 COPOLYMER WITH IMPROVED STRENGTH AND PREPARATION METHOD THEREFOR 元素驱动(杭州)生物科技有限公司 2025-05-30 WO disclosed
CN-110790906-A Method for synthesizing high molecular weight aliphatic polyester without catalyst and product thereof 浙江大学 2020-02-14 CN disclosed
US-10372047-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-08-06 US disclosed
US-20180215183-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-08-02 US disclosed
US-20180215183-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-08-02 US disclosed
EP-3355119-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA Document Solutions Inc. (JP) 2018-08-01 EP disclosed