Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 6/20 | 0.51 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16076260 | 0.87 | TRPC5 (0.51) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL16028345 | 0.87 | TRPC5 (0.60) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL16028226 | 0.86 | TRPC5 (0.56) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL18834595 | 0.86 | TRPC5 (0.65) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL16028085 | 0.85 | TRPC5 (0.47) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL16028698 | 0.85 | TRPC5 (0.67) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL16076112 | 0.85 | TRPC5 (0.55) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30171214 | 0.85 | TRPC5 (0.55) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL16028192 | 0.85 | TRPC5 (0.55) | TRPC5TRPC4KCNH2TP53TRPC1 | |
| SCHEMBL30171284 | 0.85 | TRPC5 (0.67) | TRPC5TRPC4KCNH2TP53TRPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B3 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2018-08-01 | — | — | EP | disclosed |