Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | TPH1 | P17752 | 5/20 | 0.44 |
| ▸ | TPH2 | Q8IWU9 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836795 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDMEN1KMT2ATPH1 | |
| SCHEMBL22105477 | 0.78 | MEN1 (0.68) | ALDH1A1KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL19066313 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDNPSR1MEN1 | |
| SCHEMBL13217346 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL6884105 | 0.74 | MEN1 (0.49) | ALDH1A1KDM4EHPGDNPSR1MEN1 | |
| SCHEMBL3187590 | 0.73 | TSHR (0.46) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL3103672 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HPGDNPSR1MEN1KMT2A | |
| SCHEMBL4623661 | 0.70 | MEN1 (0.52) | ALDH1A1MEN1KMT2ATPH1TPH2 | |
| SCHEMBL837415 | 0.70 | TSHR (0.49) | ALDH1A1HPGDNPSR1MEN1KMT2A | |
| SCHEMBL9393805 | 0.70 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B3 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2018-08-01 | — | — | EP | disclosed |