Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17086722 | 0.88 | HDAC1 (0.53) | HDAC1KCNH2HDAC8HDAC3HDAC2 | |
| SCHEMBL20432658 | 0.85 | HDAC1 (0.58) | HDAC1KCNH2HDAC8HDAC3HDAC2 | |
| SCHEMBL17078968 | 0.85 | HDAC1 (0.58) | HDAC1KCNH2HDAC8HDAC3HDAC2 | |
| SCHEMBL17078556 | 0.85 | HDAC1 (0.58) | HDAC1KCNH2HDAC8HDAC3HDAC2 | |
| SCHEMBL20432790 | 0.85 | HDAC1 (0.58) | HDAC1KCNH2HDAC8HDAC3HDAC2 | |
| SCHEMBL17078553 | 0.85 | HDAC1 (0.58) | HDAC1KCNH2HDAC8HDAC3HDAC2 | |
| SCHEMBL17078970 | 0.85 | HDAC1 (0.58) | HDAC1KCNH2HDAC8HDAC3HDAC2 | |
| SCHEMBL724056 | 0.85 | HDAC1 (0.69) | HDAC1KCNH2HDAC8HDAC3HDAC2 | |
| SCHEMBL1486886 | 0.85 | HDAC1 (0.69) | HDAC1KCNH2HDAC8HDAC3HDAC2 | |
| SCHEMBL20432866 | 0.83 | HDAC1 (0.55) | HDAC1KCNH2HDAC8HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116859-B1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2018-08-01 | — | — | EP | disclosed |