Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432773 | 0.89 | RAB9A (0.56) | HDAC1HDAC4HDAC8HDAC6HDAC3 | |
| SCHEMBL20433060 | 0.89 | RAB9A (0.56) | HDAC1HDAC4HDAC8HDAC6HDAC3 | |
| SCHEMBL17079053 | 0.89 | RAB9A (0.56) | HDAC1HDAC4HDAC8HDAC6HDAC3 | |
| SCHEMBL17079054 | 0.89 | RAB9A (0.56) | HDAC1HDAC4HDAC8HDAC6HDAC3 | |
| SCHEMBL20432791 | 0.88 | HDAC1 (0.55) | HDAC1HDAC4HDAC8HDAC6HDAC3 | |
| SCHEMBL18711209 | 0.84 | HDAC1 (0.56) | HDAC1HDAC4HDAC8HDAC6HDAC3 | |
| SCHEMBL722626 | 0.81 | LMNA (0.72) | HDAC1HDAC4HDAC8HDAC6HDAC3 | |
| SCHEMBL722627 | 0.81 | LMNA (0.72) | HDAC1HDAC4HDAC8HDAC6HDAC3 | |
| SCHEMBL17078988 | 0.80 | HDAC1 (0.56) | HDAC1HDAC4HDAC8HDAC6HDAC3 | |
| SCHEMBL17078990 | 0.80 | HDAC1 (0.56) | HDAC1HDAC4HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015137750-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-09-17 | — | — | WO | disclosed |