Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17078865 | 1.00 | HDAC1 (0.57) | HDAC1HDAC6MAPTNAMPTCHRM4 | |
| SCHEMBL20421035 | 0.90 | CACNA1G (0.49) | HDAC1HDAC6MAPTNAMPTCHRM4 | |
| SCHEMBL17078605 | 0.88 | CACNA1G (0.46) | HDAC1HDAC6MAPTNAMPTCHRM4 | |
| SCHEMBL17078771 | 0.88 | HDAC1 (0.58) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL17078964 | 0.86 | HDAC1 (0.59) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL18690252 | 0.85 | HDAC6 (0.78) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL17078803 | 0.85 | HDAC6 (0.78) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL20432843 | 0.85 | HDAC6 (0.78) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL17078523 | 0.84 | HDAC1 (0.57) | HDAC1HDAC6MAPTNAMPTHDAC4 | |
| SCHEMBL20420932 | 0.78 | CACNA1G (0.56) | CACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116859-B1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2018-08-01 | — | — | EP | disclosed |