Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852499 | 0.98 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL20223085 | 0.94 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL8583306 | 0.87 | TLR8 (0.81) | TLR8TLR7 | |
| SCHEMBL6416393 | 0.82 | TLR8 (0.90) | TLR8TLR7 | |
| SCHEMBL6420973 | 0.81 | TLR8 (0.91) | TLR8TLR7 | |
| SCHEMBL6128041 | 0.80 | TLR8 (0.70) | TLR8TLR7 | |
| SCHEMBL6421648 | 0.79 | TLR8 (0.91) | TLR8TLR7 | |
| SCHEMBL6421832 | 0.79 | TLR8 (0.91) | TLR8TLR7 | |
| SCHEMBL20434273 | 0.79 | TLR8 (0.73) | TLR8TLR7 | |
| SCHEMBL2854284 | 0.77 | TLR8 (0.73) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662161-B2 | Pyrimidines and uses thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-05-26 | — | — | US | disclosed |
| US-20180215720-A1 | PYRIMIDINES AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-08-02 | — | — | US | disclosed |
| US-20180215720-A1 | PYRIMIDINES AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662161-B2 | Pyrimidines and uses thereof | TYMS, DPYD, TYMP | TLR8 1078/4885TLR7 445/4885 |
| US-20180215720-A1 | PYRIMIDINES AND USES THEREOF | TYMS, DPYD, TYMP | TLR8 1078/4885TLR7 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.