⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450740 | 0.76 | SRC (0.52) | — | |
| SCHEMBL1038340 | 0.75 | — | — | |
| SCHEMBL662712 | 0.75 | — | — | |
| SCHEMBL2336389 | 0.75 | — | — | |
| SCHEMBL26067052 | 0.75 | — | — | |
| SCHEMBL4637646 | 0.75 | LMNA (0.54) | — | |
| SCHEMBL4639290 | 0.75 | LMNA (0.54) | — | |
| SCHEMBL22863330 | 0.75 | SRC (0.56) | — | |
| SCHEMBL28428 | 0.75 | SRC (0.56) | — | |
| SCHEMBL11775055 | 0.75 | SRC (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703263-A | USEFUL AS ANTIBIOTICS AND/OR AS INTERMEDIATES IN THE PREPARATION OF PHOSPHORUS-CONTAINING ANALOGS OF PEPTIDES | MONSANTO COMPANY (US) | 1997-12-30 | — | — | US | claimed |
| CN-115521276-B | F-18 marked chiral pure derivative of hydroxyfuran and preparation method and application thereof | 中山大学附属第一医院 | 2023-03-10 | — | — | CN | disclosed |
| CN-115521276-A | F-18 marked chiral pure derivative of hydroxyfuran and preparation method and application thereof | 中山大学附属第一医院 | 2022-12-27 | — | — | CN | disclosed |
| US-7956182-B2 | Process for preparing optically active alcohols | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2011-06-07 | — | — | US | disclosed |
| US-20090062527-A1 | Process for Preparing Optically Active Alcohols | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1988071-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE ALCOHOL | Kotobuki Pharmaceutical Co., Ltd. (JP) | 2008-11-05 | — | — | EP | disclosed |
| CN-1086699-C | Process for the synthesis of benzo[b] thiophenes | LILLY CO ELI (US) | 2002-06-26 | — | — | CN | disclosed |
| CN-1341596-A | Method for synthesizing benz [b] thiophenes compound | LILLY CO ELI (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1330071-A | Synthetic method for benzo [b] thiophene derivative | LILLY CO ELI (US) | 2002-01-09 | — | — | CN | disclosed |
| CN-1068883-C | Method for synthesizing ethenesulfonic acid derivative | LILLY CO ELI (US) | 2001-07-25 | — | — | CN | disclosed |
| CN-1192741-A | Vinyl sulfoxide compound and synthetic method thereof | LILLY CO ELI (US) | 1998-09-09 | — | — | CN | disclosed |
| CN-1192211-A | Process for the synthesis of benzo[b] thiophenes | LILLY CO ELI (US) | 1998-09-02 | — | — | CN | disclosed |
| CN-1192215-A | Method for synthesizing ethenesulfonic acid derivative | LILLY CO ELI (US) | 1998-09-02 | — | — | CN | disclosed |
| EP-0393607-A2 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |