SCHEMBL20436600

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29100989	0.86	MRGPRX4 (0.50)	BACE1MRGPRX4KMT2AKDM4EALDH1A1
	SCHEMBL30630386	0.86	MRGPRX4 (0.50)	BACE1MRGPRX4KMT2AKDM4EALDH1A1
	SCHEMBL25201867	0.85	BACE1 (0.41)	BACE1MRGPRX4SGMS2KAT6AMAPT
	SCHEMBL20436602	0.82	BACE1 (0.38)	BACE1MRGPRX4KAT6A
	SCHEMBL15000653	0.80	BACE1 (0.43)	BACE1TACR1
	SCHEMBL3076782	0.79	BACE1 (0.40)	BACE1KMT2AMAOB
	SCHEMBL15000893	0.78	CYP4F2 (0.45)	BACE1
	SCHEMBL31658767	0.78	MAOB (0.40)	BACE1SGMS2MAOBMAPTHPGD
	SCHEMBL29995380	0.77	BACE1 (0.39)	BACE1TACR1
	SCHEMBL29101037	0.77	BACE1 (0.39)	BACE1TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.