Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 19/20 | 0.48 |
| ▸ | DLK1 | P80370 | 1/20 | 0.46 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22723461 | 0.86 | MAP3K12 (0.46) | MAP3K12DLK1MAP3K13 | |
| SCHEMBL22753144 | 0.86 | MAP3K12 (0.46) | MAP3K12DLK1MAP3K13 | |
| SCHEMBL22723456 | 0.86 | MAP3K12 (0.46) | MAP3K12DLK1MAP3K13 | |
| SCHEMBL20437623 | 0.83 | MAP3K12 (0.45) | MAP3K12DLK1MAP3K13 | |
| SCHEMBL16216908 | 0.78 | MAP3K12 (0.78) | MAP3K12 | |
| SCHEMBL16216907 | 0.78 | MAP3K12 (0.78) | MAP3K12 | |
| SCHEMBL26604159 | 0.73 | MAP3K12 (0.48) | MAP3K12DLK1MAP3K13 | |
| SCHEMBL25147712 | 0.73 | MAP3K12 (0.50) | MAP3K12DLK1MAP3K13 | |
| SCHEMBL15743920 | 0.73 | MAP3K12 (0.50) | MAP3K12DLK1MAP3K13 | |
| SCHEMBL15743911 | 0.73 | MAP3K12 (0.50) | MAP3K12DLK1MAP3K13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018137593-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-02 | — | — | WO | disclosed |