SCHEMBL20438751

SCHEMBL20438751

CC(N)C(=O)NCc1ccc(Cl)cc1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 6/20 0.66
PRMT6 Q96LA8 6/20 0.66
CYP2C19 P33261 2/20 0.61
CYP2C9 P11712 1/20 0.61
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
RAB9A P51151 3/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
TSHR P16473 1/20 0.54
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
NPC1 O15118 2/20 0.51
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL11102143 0.98 CARM1 (0.64) CARM1PRMT6CYP2C19CYP2C9MEN1
SCHEMBL24649296 0.86 CARM1 (0.58) CARM1PRMT6MEN1KMT2ARAB9A
SCHEMBL4677340 0.86 MEN1 (0.60) CARM1PRMT6CYP2C19CYP2C9MEN1
SCHEMBL4677304 0.86 MEN1 (0.60) CARM1PRMT6CYP2C19CYP2C9MEN1
SCHEMBL8310068 0.86 MEN1 (0.63) CARM1PRMT6CYP2C19CYP2C9MEN1
SCHEMBL11294240 0.84 MEN1 (0.61) CARM1PRMT6CYP2C19CYP2C9MEN1
SCHEMBL9200501 0.84 CARM1 (0.56) CARM1PRMT6
SCHEMBL9199910 0.84 CARM1 (0.56) CARM1PRMT6
SCHEMBL24648968 0.84 CARM1 (0.56) CARM1PRMT6MEN1KMT2ALMNA
SCHEMBL30956341 0.84 MEN1 (0.59) CARM1PRMT6MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919844-B2 Antibacterials and/or modulators of biofilm formation and methods of using the same INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2021-02-16 US disclosed
US-20180215704-A1 ANTIBACTERIALS AND/OR MODULATORS OF BIOFILM FORMATION AND METHODS OF USING THE SAME INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919844-B2 Antibacterials and/or modulators of biofilm formation and methods of using the same NRDC, FIBP, BMP2 CARM1 4368/4885PRMT6 2729/4885CYP2C19 1463/4885
US-20180215704-A1 ANTIBACTERIALS AND/OR MODULATORS OF BIOFILM FORMATION AND METHODS OF USING THE SAME NRDC, FIBP, BMP2 CARM1 4368/4885PRMT6 2729/4885CYP2C19 1463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.