BMP2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL19731887	0.48	3/20
SCHEMBL11557	0.46	3/20
SCHEMBL543122	0.46	3/20
SCHEMBL18312441	0.45	3/20
SCHEMBL18313211	0.45	3/20
SCHEMBL21843053	0.45	3/20
SCHEMBL18312573	0.45	3/20
SCHEMBL18312865	0.45	3/20
SCHEMBL15616831	0.44	3/20
SCHEMBL18373332	0.44	3/20
SCHEMBL18893448	0.44	3/20
SCHEMBL8398135	0.44	3/20
SCHEMBL18494404	0.44	3/20
SCHEMBL8401261	0.43	3/20
SCHEMBL8398183	0.43	3/20
SCHEMBL8399869	0.43	3/20
SCHEMBL18312676	0.42	3/20
SCHEMBL18312866	0.42	3/20
SCHEMBL8401553	0.42	3/20
SCHEMBL8397776	0.41	3/20

Clinical trials — most relevant to BMP2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Vitamin D and Carboxy PTH Fragments in Coronary Calcification	PHASE4	WITHDRAWN
Socket Augmentation Using Atorvastatin With Or Without PRGF (Clinical and Histomorphometric Study)	PHASE4	COMPLETED
The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect	PHASE1/PHASE2	COMPLETED
A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor	PHASE1/PHASE2	COMPLETED
Parallel Study Between BMP-2 and Autologous Bone Graft After Ilizarow Treatment	PHASE1	COMPLETED
Effect of Recombinant Human Bone Morphogenetic Protein-2 With an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.	PHASE1	UNKNOWN
Double-Blind, Randomized, Single Dose Escalation Safety Study of Intraarticular Bone Morphogenic Protein (38A BMP-7) in Subjects With Osteoarthritis (OA) of the Knee	PHASE1	COMPLETED
Role of Novel Biomarkers Associated With In-stent Restenosis After Percutaneous Coronary Intervention	nan	UNKNOWN
Short-term Impact of Cyplexinol® on Self-reported Joint Pain	nan	COMPLETED
Induce XT™ Bone Graft in Foot and Ankle Fusion	nan	ENROLLING_BY_INVITATION
Osteogenic Profiling of Normal Calvarial Bone	nan	COMPLETED
Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response	nan	COMPLETED
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies	nan	UNKNOWN
Regenerative Therapy of Periodontal Bone Defects	nan	UNKNOWN
Transcription Factor Runx2 in Necrotic Femoral Head Tissue	nan	COMPLETED
Immediate Implants in Maxillary Premolar Region Using Xenograft vs Allograft	nan	UNKNOWN
Early Regenerative Intervention for Post-Traumatic Osteoarthritis	nan	UNKNOWN
Assessment of Guided Bone Regeneration in Atrophic Anterior Maxilla	nan	UNKNOWN
Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier: An In Vitro Analysis	nan	NOT_YET_RECRUITING
Evaluation of the Osteoinductivity of Atorvastatin Combined With β-TCP	nan	NOT_YET_RECRUITING
Genetic and Environmental Characteristics of Primary Pulmonary Hypertension	nan	COMPLETED
Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Combined With Injectable PRF Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation	nan	COMPLETED
AO CSH Mainstream Study on Cervical Spine Degeneration	nan	NOT_YET_RECRUITING
Effect of BMPR-2 Gene Mutations on Hemodynamic Response by Iloprost Inhalation in Pulmonary Arterial Hypertension	nan	COMPLETED
Assessing Safety of Cervical Spine Fusion With NMP®	nan	NOT_YET_RECRUITING
The OsteoStrand Plus Deformity Study	nan	UNKNOWN
Artificial Intelligence-Enhanced Three-Dimensional Reconstruction of Ridge Deficiencies	nan	COMPLETED
Clinical Study of Injectable Ceramics Bone Graft Substitute Containing rhBMP-2	nan	COMPLETED
Efficacy and Safety of Novosis Putty for Degenerative Lumbar Disease	nan	ACTIVE_NOT_RECRUITING
Pilot Study of rhBMP-2/BCP in Patients With Spinal Degeneration With Instability Requiring Surgical Fusion	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a BMP2 binder may also engage these)

Protein	Name	Similarity
P21274	—	1.000	P21274 →
O46564	—	1.000	O46564 →
O19006	—	1.000	O19006 →
P49001	—	1.000	P49001 →
Q90751	—	1.000	Q90751 →
Q06826	—	1.000	Q06826 →
Q2KJH1	—	1.000	Q2KJH1 →
O46576	—	1.000	O46576 →
BMP4	Bone morphogenetic protein 4	1.000	landscape →
Q29607	—	1.000	Q29607 →
Q90752	—	1.000	Q90752 →
P21275	—	1.000	P21275 →
P25703	—	1.000	P25703 →
Q804S2	—	0.999	Q804S2 →
P30884	—	0.998	P30884 →
Q8MJV5	—	0.998	Q8MJV5 →
Q9Z1W4	—	0.998	Q9Z1W4 →
Q9UK05	—	0.997	Q9UK05 →
O95390	—	0.996	O95390 →
P30885	—	0.995	P30885 →
Q9Z217	—	0.995	Q9Z217 →
Q4AEG6	—	0.995	Q4AEG6 →
P85857	—	0.994	P85857 →
P34822	—	0.994	P34822 →
O95393	—	0.993	O95393 →
Q07104	—	0.993	Q07104 →
P27091	—	0.993	P27091 →
Q9WV56	—	0.992	Q9WV56 →
P35621	—	0.992	P35621 →
P48970	—	0.992	P48970 →