⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108375 | 0.76 | — | — | |
| SCHEMBL24782 | 0.72 | — | — | |
| SCHEMBL13009507 | 0.69 | FFAR3 (0.47) | — | |
| SCHEMBL30831806 | 0.69 | FFAR3 (0.47) | — | |
| SCHEMBL27950788 | 0.69 | — | — | |
| SCHEMBL22167685 | 0.69 | — | — | |
| 2,3-Pentanedione SCHEMBL1514922 | 0.67 | ALDH1A1 (0.53) | — | |
| SCHEMBL6393264 | 0.67 | — | — | |
| SCHEMBL198248 | 0.67 | ALDH1A1 (0.44) | — | |
| Potassium Ion SCHEMBL3483407 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673676-A | Pyrimidoisoquinoline derivatives useful for treating allergies | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-16 | — | — | US | claimed |
| EP-0143001-A2 | Pyrimidoisoquinoline derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-05-29 | — | — | EP | claimed |
| US-4264613-A | Piperidylbenzimidazolinone compounds | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1981-04-28 | — | — | US | claimed |
| EP-0008259-A1 | Piperidyl-benzimidazolinone derivatives, processes for their preparation and pharmaceutical compositions containing them | SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1980-02-20 | — | — | EP | claimed |
| US-7956182-B2 | Process for preparing optically active alcohols | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2011-06-07 | — | — | US | disclosed |
| EP-2042502-A1 | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2009-04-01 | — | — | EP | disclosed |
| US-20090062527-A1 | Process for Preparing Optically Active Alcohols | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1988071-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE ALCOHOL | Kotobuki Pharmaceutical Co., Ltd. (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1544199-B1 | NITROGENOUS CONDENSED-RING COMPOUND AND USE THEREOF AS HIV INTEGRASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2008-10-15 | — | — | EP | disclosed |
| US-20080161311-A1 | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. | 2008-07-03 | — | — | US | disclosed |
| US-7211572-B2 | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2007-05-01 | — | — | US | disclosed |
| US-20060052361-A1 | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. | 2006-03-09 | — | — | US | disclosed |
| EP-0224919-A2 | New thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |
| US-4264613-A | Piperidylbenzimidazolinone compounds | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1981-04-28 | — | — | US | disclosed |
| US-4264613-A | Piperidylbenzimidazolinone compounds | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1981-04-28 | — | — | US | disclosed |
| EP-0008259-A1 | Piperidyl-benzimidazolinone derivatives, processes for their preparation and pharmaceutical compositions containing them | SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1980-02-20 | — | — | EP | disclosed |
| EP-0008259-A1 | Piperidyl-benzimidazolinone derivatives, processes for their preparation and pharmaceutical compositions containing them | SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1980-02-20 | — | — | EP | disclosed |